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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab454a85c382428f1c7bdd51708c318c14528a8dfe03d7c06653aa9994c3c508' 
  AND token = 'OtB74x0HVana64kNPUz7CVAutaQ+QDuFxPlaJrabC48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}