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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a6980832156b63b47610d6716c09a1f039d5652dc521586fd5c70b1c495da0' 
  AND token = '+5KW5B1KEcKKwjbdqrHwR+FjCSJv5QcpCnYS24az5LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}