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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7db4dcb8f2e891e650e315c4d8569c518707f594eb5c5b0e596ebf4b63b5bce' 
  AND token = '+5/XaZ+BAW5q14HRnhvzQsVhSIz7eLKgSeyqlbA8Va4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}