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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e19310d6636eb7ec842f16fff695b58d045b1b2bd5085b9289ed6128335c1335' 
  AND token = 'zxzmxsdSzTM2I5Ghi1HxiCmmQ9nsBKuY3JaXSgBsm1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}