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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4feecb391a81e9acaa4ec3b71ad96f07f24cd8a27d6103e7e43687b63ac8400' 
  AND token = 'hiXHPuvkEn6AiNIVvvX8s0lI6MRzJcSrrqbf2BCsPdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}