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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc8b04ecfa39a6180e2f4be5cdd05a86681294720ede2ee27f508edf6d65d1d8' 
  AND token = 'Oo41vZA19O3Ae/NcSq9ltG0AnV+wyyPFrgik8bs/G74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}