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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c4d8c2090005c9b57370f5f4cb9075a399a5e53479c8c1494971d2d4c3b43b' 
  AND token = 'uCrdsXRZ23/5mOaw+ykC0U4cJmMF+7rNpEO/Iq1d97M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}