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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308c8a4eb61df2c5edd09661e5d749f0010e283cf233be96ff1af52f0de0fbb8' 
  AND token = 'njut/AD5hF54c++Gk3dkUP84sojDXwwidZV+IM6xz8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}