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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c86037449a59170aeb60b6ecc6359a4ad043f4094df8df98ff17a649ae0de0' 
  AND token = '+7PN/hMW2oZIK9LeD1Q1rjCIPvMmF/ZunxLmylteMeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}