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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c37e35c6e4435ee1415146e9e572206180ca342f239f6e37184108e60561675' 
  AND token = '7ufd+bNZgTWNus/HMysm39iXKWlwCx/2XJqZ/hUrndo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}