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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ff40aa08f2925f67031defab28658528461df5ed2ecb8b6bf306edc48a60ee' 
  AND token = 'X2r5sVRhB98r7BwQt2zfc9YIvBXVKrqfon4DzRxJwx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}