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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde1e16fc6012bd4efcae44a372df3ce77556cc4d7276e795f4c90db3e858547' 
  AND token = 'HRUzTseB+GwANScdALVSBN9qo0rdDW657kX9HB0Y4DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}