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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57a8d03b6400a76d6b042df4235e055bac8b9ba18a0cb9c18f2f6399a1890dd8' 
  AND token = '+Z0ubMYPZOWrcapBvx1pBADPgpRnk0aVXm4L+/2kqQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}