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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f29f45abc11e2837ec187527e73696da35beecd80c3ce7533c4199f6f33e03' 
  AND token = '+jZatln01wXzGdvc2jeZQ1BJ5v+SpSJWFXPISCzkZHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}