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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef223260f486dd6a494bc7f3cd4962547673bfbe1195cc2b9f098e1e57953308' 
  AND token = 'v6/7dJYw4+iv9MDQrDHreOMlFHhIhkSdFsmr3RmnpDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}