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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b161c0d5e858d69b259b7ded2865a4339908054d2623332bbb4ca00ace3f5dcf' 
  AND token = 'sIx0v6vi1Nj3/LvMNrJ7Y3gvGj7k+5HurJnMzxpR5Wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}