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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a9bb9b4f369c81c57040834b2a9573cd727b8bb6064bb806c7b21b3dce96db5' 
  AND token = '9dcSkNMFMsLx9osTczobdMx/eJH1CMQGatKDSCc6Iks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}