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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4072694f879dcd3641ec7d0dcfa3f4590abbb585c9735f68d57c64e591b79a9' 
  AND token = '+JPwyIo1myUvk+CJtT3a1fE5n3jfkuJtS/JY8YCkiTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}