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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dede445c6ff19c6b1b93b2df4c252dabb7f3b65613bae4fa4c441b710449ad93' 
  AND token = '/UYl1UXW3JieSFzSB9zmuhIj1DMgl0HbEQx+l/xgSXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}