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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8429630da76df9242af107d2a1720d7f557ecf320c4e2ee755dcfd53f21301' 
  AND token = 'm6mh/UvK/m84hpdh6X8+UambqP1a6oCQsdCfE1eL/Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}