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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa50cfb83ee5339131f70d3d7b9b1fb2ffa05eff7dbcf6b0c3c1201446585e33' 
  AND token = '5Y1ynDDrvriUKdUIbQpEvXMM++wwh/uLYcfRJPmNCOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}