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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a39a5c5316dd920e70eadb00d9aea7a2e1c8cbf59d40ece634d0f9143cdaab' 
  AND token = 'XqNlNa/BYLOh8YqXIk/4IP9p0Z120lpUY6UgGvE6Z5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}