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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e54c4b0c48f49b5a692c7d4a394b1b38a855ba4dace319a6be2e1294b21b496f' 
  AND token = 'ArBXH1TBKM6uS+qt2890L7LuZ68FWKhoQtWzcRMstnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}