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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6a1e16e8682c26b2aa4cfb1699d890d15981a7d5811e69a515e4c49b3182cb' 
  AND token = 'v+1w9k672I6yWG/rA88Fw1c3OAgsuw5KIvZ///kSyHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}