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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '466d91d032e6df6ded53702878814831b14615108b707d610cdd4c731d5b2f81' 
  AND token = 'lp+NWprAg1CjaU1lSQbkq/IUxCdPw96Dw7VdKMcBuSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}