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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219158bc56cf3fd3ad9f81511dab4bc9c73e89b68039d4d6b78f0a236156e929' 
  AND token = 'D4HBc2h42vOFmB3659o4QtAzP45NgmyQxPFINy4UEec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}