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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4237b60f49672c24020ce8b01c1e2a90cc1f9d0f6ebed2be44a773fb5a56b887' 
  AND token = 'PaRhJB7ZVtlyezRM0atTX8AHRJUDFPZfYeKzjpd72vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}