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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d366e33d201db122ff635b4879e515102eda66a14e220ad7d7ecce8b2c77a30' 
  AND token = 'F9Fe9QwHhg51Np/f946S2GVch5PBhauwHAhPA20dTIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}