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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a045a72dabffa561f52c909834f4a33d95df8be19a8b9e65afdeff31786fa38b' 
  AND token = 'E9KDIEysF5/bQvS0CoO5r/cuxOjgQq0C+iXdeLibaT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}