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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f7c5f626adeba477458f9bb6887aebf53f9837e32cefa309dfb34a0a90a159' 
  AND token = '9GNo2+fT6NTy8GZNSCXS9p60E/wzjOzNKGC5mZjdLyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}