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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9a110f19ea28efc9adf4b44a517a12371ebd0fe4563b2fdab1599d391fb4850' 
  AND token = 'CWBsr6pc7wxIHbMyb2YqJ4IB2MIj0TIdyle0qqdxBw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}