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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3b8ea74779cf381265c9ae9d2d0b7075da2d5b826196eb380df429c70e206aa' 
  AND token = 'u0BhhixxiU9g4qS7/7DdpXZU6RKrFJtVEgmKEcu8ECs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}