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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2666a4408be5d15f87aa4113bb69382950283de067b743f5d6d1c04d302ed95' 
  AND token = 'qN53ryhw3M15wbP5pzjxnLp+qhDvHQe9sEhT5ksPbCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}