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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9948b44c2f833454aaba701ac9ae7c951877f3b89a86f98a83d1d1284cd5faca' 
  AND token = 'o0L8KcpBVDOIoSyDhBCPE8esqXC+IF49oPY8wgCcsBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}