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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133b67dc1855cdaf61605c6b42a62b47f3bd45b7e5104ae8d77614983433e0fc' 
  AND token = 'GjkSJEMyp5Kfd8j366v9BJ7AfOpIzniP3lCk5fqq2XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}