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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79e30a0d366661138afb8bda4a625826f0e5a252dc942d4d2fe6edae418b6027' 
  AND token = 'HYtAxgyCM423Fek2JvmbcKuq1r1xnCzwOHTbQXUxkdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}