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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b78931b868347bc1c5a4a15c3c3a995221d17d22e888eaf98222c33472f458' 
  AND token = 'fJqlMU+0H47jwNm4hMC64oVH2jpmCVsS9ohMpOq3f0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}