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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82771dd9404881825aa72d9e7080ea2ee1fc15e500429f8b2d8afea44a6b188f' 
  AND token = 'SSNE5wcHKnLJpm7x79+d+oACEWrLB6Dr8RV1GSGXG00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}