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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc5c4f207027c17483c10d59cf51db248e6a0b106e351bfe96621b6cd20b7c2' 
  AND token = '7HqgpsaV1QwPE0UNudP1AsksPOPtsQ0hwHw5jg1bFeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}