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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3d38f6bcd1a453d6615482da68fa3822714133e66dc08acb8ff50195279c1a' 
  AND token = 'yTHeXo14JCc4LdDrLco6g5ujQkCCO2A/tRxjPonoy0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}