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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7893c2a6b9008a3bf8a65bb50c63e70a23d69b1158425ab5764741fca35ceda2' 
  AND token = 'IVZvH55xHz/so0XlcsyARVW5kQV6eEvVMjwz/5oLl70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}