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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acd0c7b6cb8129efc1dc4413794d2dc5b3acba7b99483e8ad007606bda1bf38' 
  AND token = 'f7x6shD0ufzR138ID7nd2H7wTOM+Pjxqp5qG2n9QMU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}