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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3072f6645a41ca5ca5ef659a97a17d1937e4beef77aeb6f7679bc21a8016b82d' 
  AND token = 'oGfM6dU9xcikU/C+sOFju8j8KCSUNN2UEUGI4vvPzA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}