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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61fb500646491f5b5e1345e35d99d9c06e7923969a36a385b137696365e4371' 
  AND token = 'JjGWUwMeQcc3Vzl7bpzuwGuBPfBJXA53YTRIIpHenZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}