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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '993d655ec4bb357924d84c651d2647a1604495c1f7096d0cf99189b32f36a6e9' 
  AND token = 'utZ04XAncrwi9yL/2vye7mtCuEP+t4quavlJJ+InFCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}