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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bc3698f30e8eb63387a2ead9f180f2f3b66d419ff410f62ad933400eeb04bf3' 
  AND token = '6KkYdH17SuA7RK02EOmHG2IXSt5IyxZyejnTlga1nyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}