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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f562a04cf7d3881ecd09e783508c2f9cbf54e6a9e718d9776890bdab9e7d049' 
  AND token = '3Ac8TH/4RZgAxEIZVQrzyu4FF5CBro1ChI037gTfaKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}