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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae7b66136b20a1efbc4a0a9b288e2c1a82003e10135a091734291bf4e39a6772' 
  AND token = 'Q2K0qBf7fC9anE//HdoIWh4/h/aF0J6haIlDHDyvBDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}