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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e24d5d36c56bb1878fb6c31d7c7c30abb816bcb3695c026e7d8d83db322a5a58' 
  AND token = '3IoeDIG0N718aoRZlXlK+nJnJwBVpsgHd7Wi3R3BIjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}