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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e62f50bc8a7df3fe81f6c9f850f654fdda9e3edd0dd40b31b1754d7b42fcce9' 
  AND token = 'fKH4qknTEHI+bN5t9ReZGGBIGAvy6O+o3mxgF5DT0fI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}